Dimpropyridaz (dimpropyridaz)

Dimpropyridaz (dimpropyridaz) is an insecticide developed by BASF. It is the first active ingredient to represent IRAC Group 36, classified as a new mode of action for the control of sucking and chewing insects.

Common name (ISO): Dimpropyridaz (dimpropyridaz)

Synonyms: Axalion (trademark of the molecule); Efficon (commercial product brand)

Gross formula: C16H23N5O

Number CAS: 1403615-77-9

Chemical class: Pyrazolecarboxamide (pyrazole carboxamide)

Main patent: WO2012143317

Dimpropyridaz development began in 2006, following BASF's acquisition of American Cyanamid. Initial screening of the obtained chemical compound library identified a compound with promising insecticidal activity. This compound, although initially low in potency, served as the starting point for the development of the new class of PPC insecticides.

Between 2006 and 2011, the company conducted research to optimize the chemical structure of the initial compound. A major milestone was the replacement of the pyrazole moiety with a pyridazine, which significantly increased insecticidal activity, especially against whiteflies (Bemisia tabaci). This chemical refinement led to the identification of dimpropyridaz.

From 2012 onwards, the product was further refined technically. Synthesis processes and initial formulations for practical application were developed (WO2012143318). Improvements were also made to product stability (WO2014144308).

In 2018, the ISO common name "dimpropyridaz" was officially approved by the ISO Committee on Pesticide Nomenclature.

Registration processes began in several countries in 2019.

Mode of action

Dimpropyridaz exerts its insecticidal activity by inhibiting the firing of the chordotonal organ and thus disrupting the function of the chordotonal organ.

Characteristic symptoms of pest infestation include disruption of sensory perception and motor coordination, resulting in the insects' inability to feed adequately.

The time required for symptoms to appear varies depending on the species and environmental conditions, and specific information from efficacy studies is required for accurate data.

Control spectrum

Dimpropyridaz has been shown to be effective in controlling:

• Aphis gossypii

• Bemisia tabaci

• Brevicoryne brassicae

• Dalbulus maidis

• diaphorina citri

• Empoasca kraemeri

• Frankliniella schultzei

• Rhopalosiphum maidis

• Sitobion avenae

• Tabaci Thrips

Due to its unique mode of action and recent introduction to the market, there is still no extensive documentation on species naturally tolerant or resistant to dimpropyridaz.

Technical recommendations

The commercial product Efficon Contains 120 g/L of dimpropyridaz. Specific doses vary depending on the crop and target pest, and official technical recommendations for each local register should be consulted.

The ideal time for application should coincide with the onset of sucking pest infestation, preferably during the juvenile stages of the pests to maximize effectiveness. Regular crop monitoring is recommended to determine the optimal timing.

Applications should be made in conditions of low relative humidity, absence of strong winds, and moderate temperatures. Avoid applications during periods of severe plant water stress or in conditions with a high probability of rain in the first hours after application.

Mixtures to avoid

Due to the specific chemical characteristics of dimpropyridaz, avoid mixing with highly alkaline products or products that may cause hydrolysis. Specific incompatibility information requires consultation with specialized technical literature.