Cyproflanilide

Cyproflanilide is a synthetic insecticide developed for agricultural pest control. It acts against lepidopterans, coleopterans, and thrips.

It was registered in China. Patent applications for the compounds have been filed in more than 10 countries, including the United States, Japan, Brazil, and Germany.

Common name (ISO): Cyproflanilide

Synonyms: CAC-I-785 (development code); Baishijia (commercial product trademark)

Gross formula: C28H17BrF12N2O2

Number CAS: 2375110-88-4

Chemical class: Meta-diamide (subclass of diamides).

Development history: Cyproflanilide was developed by Nantong CAC International (CAC Shanghai International Trading Co., Ltd., China) as a homegrown bisamide insecticide based on bisamide meta-diamide structures. It was patented in China in 2019 and is in the process of international registration. In 2021, Syngenta and CAC Nantong entered into an agreement involving the molecule in China. In 2024, UPL Corp. Enters Into Agreement with CAC Nantong for global marketing. 

Mode of action: Allosteric modulator of gamma-aminobutyric acid (GABA)-activated chloride ion channels, classified in IRAC group 30 (allosteric modulators of GABA-activated chloride channels). It acts by inhibiting nerve transmission in insects, leading to paralysis and death, and is effective against populations resistant to other insecticides.

Patent numbers: CN 108586279, US 20200178525 and others.