Benzovindiflupyr (Benzovindiflupyr)

Benzovindiflupyr (Benzovindiflupyr) is a broad-spectrum fungicide developed by Syngenta, used primarily to control fungal diseases in agricultural crops such as cereals (wheat, barley, oats), corn, soybeans, fruits, vegetables, and ornamental grasses.

It is applied via foliar application or as a seed treatment, offering long-lasting protection against pathogens such as rust, mildew, leaf spots and anthracnose.

Common name (ISO): Benzovindiflupyr

Synonyms: SYN545192 (development code); Solatenol (trade name for the molecule)

Trademarks containing benzovindiflupir: there; Elatus Easy; Miravis Trio WG; Vessarya and others

Gross formula: C12H15Cl2F2N3O

Number CAS: 1072957-71-1

Chemical class: pyrazole carboxamide, belonging to the FRAC group 7 (Succinate Dehydrogenase Inhibitor - SDHI).

Development History: Benzovindiflupyr was developed by Syngenta as part of a research program for next-generation SDHI fungicides, aiming to overcome resistance limitations in previous fungicides such as boscalid and fluxapyroxad. Research began in the late 2000s, focusing on molecules that inhibit fungal mitochondrial respiration more selectively and lastingly. Field trials in Europe demonstrated its efficacy against a broad range of fungi in cereals and other crops. It was first registered in the European Union in 2013 under Regulation EC 1107/2009, with subsequent approvals in countries such as Morocco, Canada (2015), and the USA (2015).

Mode of action: Benzovindiflupyr acts as an inhibitor of succinate dehydrogenase (SDHI), a key enzyme in the fungal mitochondrial electron transport chain. It binds to the ubiquinone site in complex II (succinate:ubiquinone oxidoreductase), blocking cellular respiration and ATP production, leading to the death of the pathogen. Its translaminar movement (penetration through the leaf) provides internal and external protection to plants, with a high affinity for fungal lipids. It is effective against ascomycetes, basidiomycetes, and deuteromycetes, but does not directly affect plants or mammals due to selectivity. Studies show reduced leaf transpiration in treated plants, a non-fungicidal side effect that may improve water retention under stress conditions.

Patent numbers: WO2011131545A1 (synthesis method and fungicidal composition, published in 2011); WO2011131544A1 (related compounds and agricultural uses, 2011); WO2011131546A1 (structural variations and formulations, 2011) and others.