Syngenta informs about the launch of Equento

Syngenta Crop Protection announced the launch of a product under the Equento trademark. It will be used in seed treatment. The active ingredient in question is isocycloseram, already launched in Brazil under the brand name plinazolin.

According to information from the company, the product alleviates increased resistance to insects, while offering control of a wide variety of soil pests. This seed treatment can be applied to various crops, including cereals and canola.

Also according to the company's statement, this seed treatment is effective at low doses and is not easily soluble or mobile in the soil. It is effective even at low soil temperatures, controlling pests that ingest or come into contact with the plant and reducing pest populations in the soil.

Syngenta will launch Equento globally in Australia later this year. More registrations are expected in other markets.

The Equento brand is currently registered in: Algeria; Australia; Canada; Kazakhstan; China; Egypt; U.S; Russian Federation; Morocco; Mexico; and Ukraine.

See also: Anvisa approves new isocicloseram-based products.

Learn more about plinazolin (isocycloseram; isocicloseram)

Plinazolin is just a trademark. The molecule is called isocycloseram (isocicloseram; CAS 2061933-85-3) and belongs to the group of isoxazolines (isoxazoline). It consists of an insecticide and acaricide with action against species of Lepidoptera, Hemiptera, Coleoptera, Tisanoptera and Diptera.

According to internal information from Syngenta:

"Isocycloseram selectively targets the invertebrate Rdl GABA receptor at a site distinct from phenylpyrazoles (fiproles) and organochlorines. The widely distributed cyclodiene resistance mutation, A301S, does not affect sensitivity to isocicloseram, either in vitro or in vivo, demonstrating the suitability of isocicloseram to control pest infestations with this resistance mechanism..

Detailed studies have demonstrated that the binding sites relevant to the insecticidal activity of avermectins and isocycloseram are distinct. Isocycloseram has been shown to compete for binding with metadiamide insecticides related to broflanilide.

Furthermore, a G335M mutation in the third transmembrane domain of the Rdl GABA receptor impaired the ability of isocicloseram and metadiamides to block the GABA-mediated response. As such, the Insecticide Resistance Action Committee (IRAC) has classified isocicloseram in Group 30 'Chloride channel allosteric modulators with GABA control'".